Structural Biology Services

Structures of proteins and protein complexes provide ultimate insights in atomic resolution to their function. From gene synthesis, high purity protein preparation, crystallization screening and protein folding analysis by NMR, all the way to protein structure determination, we provide a comprehensive service platform for structure biology. We offer two complementary approaches, X-ray crystallography and Nuclear Magnetic Resonances, for protein structure determination, protein complex analysis and the probing of protein dynamics. Together with our experienced partners, we provide reliable and resourceful services and consultations based on our extensive experience and deep knowledge of protein structure/function relationships.

Proteins produced for our structural biology service platform are of “structure grade” with purity >95%, ready for crystallization, NMR analysis and other downstream assay development applications. Our proprietary CT-XtalScreen process offers parallel screening of crystallization conditions resulting in diffraction grade crystal for high resolution X-ray crystallography, suitable for structure-based researches, support your lead optimization and fragment based discovery programs. Our CT-Isotope 15N/13C isotopic labeling process produces proteins ready for NMR analysis, facilitating protein folding, dynamics, complex formation and structural analysis by NMR spectroscopy.

 

Key Features:

  • Comprehensive platform: Services cover all stages of structure determination-from gene synthesis, high purity protein production, crystallization screening to structure determination
  • Complementary technologies: Achieve better understanding of protein folding and function through structure analysis by X-ray crystallography and/or NMR spectroscopy
  • Structure-function relationships: Probing the detailed correlation between structure and function through structure, complex and dynamics analysis of proteins

 

Service List:

  • CT-Function CrystalClear Structure Service: We offer a milestone based structure determination service by X-ray crystallography. The progress of every project is evaluated at each milestone point and communicated to the customer in a timely fashion. Delivery timeline is project dependent. More...
  • CT-Function SAR-By-NMR Service: Nuclear Magnetic Resonance (NMR) is a technique for solving protein and nucleic acid structures as well as evaluating protein dynamics and complex formation. We offer a milestone based structure determination service by NMR spectroscopy, Structure-Activity-Relationships-by-NMR, with options for protein compound binding screenings. The progress of each project is evaluated at each milestone point and communicated to the customer. Delivery timeline is project dependent. More...

 

Related Products:

•  Codon Optimization and Verification •  mAb Library Service
•  Gene-to-Antibody Service •  Protein Blotting/Staining System

 

 

Quotation & Ordering:

  • For quotation requests and questions, you may contact us by email, phone, or via our secured online message system.
  • To order, simply fill out the order/quotation form and submit to: order@protein-ct.com. Orders can be placed by phone, email, fax, or online with a formal PO (Purchase Order) . You may contact us anytime for assistance.

 

 
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